Thursday, February 25, 2010
enzimnoni-mengkudu | 12:35 AM |
Dr. Ralph Heinicke pioneered the study of the alkaloid Xeronine. Xeronine is produce in the body from the building blocks Proxeronine and Proxeronase. These building blocks are abundant in the juice of the Morinda citrifolia fruit.
Xeronine is a relatively small alkaloid that is physiologically active in the picogram range. (Editorial note: a picogram is one trillionth of a gram.) It occurs in practically all healthy cells of plants, animals and microorganisms. However, the amount of free alkaloid is minute, and is well below the limits of normal chemical analytical techniques.
How Fed Noni Enzyme Can Fight The Cancer?
Main components was found in Noni that can reestablish body cell to fight cancer is Xeronine. It is also call "dry alkaline compound" which is found in found in green fruit. One of them is noni fruit.
Fed Noni is 100% pure natural noni enzyme and based on survey conducted by Dr Neil Solomon to about 886 people where 50 are doctor and the rest are cancer patient respondent, the result show about 65% of them give positive feedback and very effective result. Cancer patient are among prostate, breast, colon cancer and etc. Study or survey was done in 1999.
As a researcher in Hawaii, Dr. Ralph Heinicke became aware of the marvelous benefits of the Noni fruit and set out to find the pharmacologically active ingredient of the Noni. Dr. Heinicke had spent over 45 years studying the effects of an alkaloid he discovered and named xeronine.
Xeronine is a relatively small alkaloid which is physiologically very active and important for the proper functioning of all cells in the body. In his research, Dr. Heinicke discovered that the Noni juice contains appreciable amounts of the precursor of xeronine that he named "proxeronine". "Proxeronine" releases pure xeronine in the intestines when it comes in contact with a particular enzyme also found in the Noni Juice.
Dr. Heinicke's theory is that, when released, xeronine actually works at the molecular level to repair damaged cells. Dr. Heinicke states that the primary function of xeronine is to regulate the rigidity and shape of specific proteins. Since these proteins have different functions within the cells, this explains how the administration of Noni Juice causes an unbelievably wide range of physiological responses. "Some of the problems which drinking Noni Juice might favorably affect are: high blood pressure, menstrual cramps, arthritis, gastric ulcers, sprains, injuries, mental depression, senility, poor digestion, atherosclerosis, blood vessel problems, drug addiction, relief of pain, and many others. Although this list looks like a page torn out of a traveling medicine man's manual, it is probably conservative." - Dr. Heinicke
When Ralph M. Heinicke received his doctorate in biochemistry from the University of Minnesota, he wanted to escape from those cold Minnesota winters and so he took a job with Dole Pineapple Company in Hawaii. His first assignment was to develop a method to extract the enzyme that caused pineapple to prevent gelatin deserts from setting up. He found it was an enzyme called bromelain and in due time he and his coworkers found a way to extract it. Soon the Dole Company found that every day they had over a thousand pounds of this crude bromelain enzyme extract left over as a waste product. At the time it had no commercial value, and so the company president asked Dr. Heinicke to see if he could find some use for this material. Eventually he found it was a proteolytic enzyme that had some medical applications. He worked with Smith-Kline and the Rohr pharmaceutical companies to expand its medical use.
In order to get FDA approval for this enzyme he had to refine the crude bromelain extract down to an extremely pure protease enzyme. Much to his and the drug companies amazement, the more pure the enzyme became, the less beneficial it was in many of its applications. Eventually, in its purest state, it had only 5% of its original potency for many of its uses. Dr. Heinicke was then asked to find what it was they were removing that had given the crude bromelain extract all of its power. Meanwhile the giant Japanese drug company Toshiba had also launched a 3 year, 3 million dollar program to find the same answer. At the end of that time they had used up all their money and not found the answer. Not one to give up easily, Dr. Heinicke continued his research and eventually found to his great surprise that the active ingredient was not a protein, carbohydrate or fat, but a substance known as an alkaloid.
Alkaloids are one of the most important classes of phytochemicals known, and are a major source from which many modern medicines are drawn from Nature. By isolating this alkaloid into a pure state, he was able to identify is exact chemical structure. Because it could be reduced to a dry crystalline structure he decided to use the latin prefix "Xero" meaning "dry" as the first part of its name. Since it was also an alkaline compound he tacked on the suffix "ine" indicating its alkaline nature. When the prefix and suffix are combined it gives us the word "Xeronine" which means, "a dry alkaline compound". Which is the descriptive name he chose for the compound he discovered.
Eventually he found that Xeronine was a very important biochemical in the human body and essential for good health. So essential that the human body has a limited ability to manufacture it from the raw material found in certain fruits. Like many other biochemicals produced in the body, he found that positive thoughts and emotions, along with exposure to art, music, nature and spiritual experiences increased its production. While negative thoughts, emotions and stressful experiences suppressed it's production. He also learned that as the body's level of Xeronine declined with age, stress and a poor diet, the level of health and recovery declined right along with it.
PHYTOCHEMICALS REVERSE CANCER
The power of phytochemicals to promote good health and control cancer is so impressive that the University of Illinois has created a whole new department with 63 scientists and professors to specialize in phytochemical research! Let me share with you some of the scientific findings leading to this major change in research.
Senior Science Advisor to the U.S. Public Health Service, Dr. D.L. Davis states, "Phytochemicals can take tumors and defuse them. They can turn off the proliferative process of cancer." At Ohio State University's Cancer Prevention Laboratory, Dr. Mark Morse and colleagues found that phytochemicals in broccoli known as sulforaphane could reduce esophageal tumor incidence by as much as 40% and reduce the multiplication of such cancer cells by 90%. Dr. Paul Taladay working at John Hopkins Medical Institute has found that this same phytochemical protected animals from getting cancer even when exposed to cancer causing chemicals. According to Dr. Joseph Hotchkiss of Cornell University, University, the phytochemicals coumaric acid and chlorogenic acid are able to eliminate many cancer causing substances from the body. An epidemiologist at the University of Minnesota, Dr. John Potter, told Newsweek Magazine, "At almost every step along the pathway to cancer, phytochemicals slow up or reverse the process." Most of these phytochemicals studied so far are found in ordinary vegetables and culinary herbs. The problem is the amount in these foods is so low that only if you eat a lot of them for a long time will they give you protection. If you already have cancer, what you need is a plant that has these phytochemicals in large enough amounts to go right to work.
NONI IS A TREASURE CHEST OF PHYTOCHEMICALS
When plant scientists at the U.S. Department of Agriculture studied the amazing Noni plant they quickly found the secret to its amazing health building power. It is endowed with a greater number and variety of health giving phytochemicals than just about any plant known. Dr. James A. Duke is one of the world's most highly respected scientific authorities on herbs and their phytochemical content. In his authoritative CRC Handbook on Phytochemicals he has listed 23 different phytochemicals found in Noni as well as 5 vitamins and 3 minerals. Research on Noni continues at an ever increasing pace with more of its phytochemicals being uncovered all the time.
IT IS THE INCREDIBLE POWER OF THESE PHYTOCHEMICALS THAT ARE PRODUCING THE WONDERFUL HEALTH BUILDING RESULTS DOCTORS AND PATIENTS ARE NOW SEEING AS A RESULT OF USING THIS AMAZING FRUIT! AS SAFE TO USE AS ANY FRUIT ON THE MARKET
The U.S. Food and Drug Administration, as well as the Department of Agriculture maintain a list of plants that have no known harmful ingredients and which over the test of time with large numbers of people have proven themselves to be safe for human consumption by the general population. This is known as the GRAS list, and it stands for Generally Recognized As Safe. Based on the fact that after careful scientific analysis no harmful ingredients were found, and the Polynesian people have been using this health building herb without harm for thousands of years, NONI HAS BEEN OFFICIALLY DESIGNATED AS GENERALLY RECOGNIZED AS SAFE.
Even though Noni is extremely safe, I would always suggest that the introduction of a new herb into the diet be approached with caution by anyone known to have food sensitivities, allergies, or asthma. I would also caution a woman who is pregnant or nursing to consult her physician before using Noni or any other herb.
HOW NONI HELPS THE BODY FIGHT OFF CANCER
Researchers at the University of Hawaii School of Medicine introduced cells containing a strain of lung cancer known as Lewis Lung Carcinoma into a group of mice especially bred to be highly susceptible to this type of cancer. Within 9 to 12 days the mice which were given no Noni were all dead as a result of the growth of the tumor. However, another group of these same mice were given an extract of the Noni fruit on five different occasions. At the end of the 12 days when all the untreated mice were dead, those given the Noni were still alive and doing well! At the end of 24 days, the Noni treated mice were all still going strong, this was a 100% extension of life! Actually, 40% which is 9 out of the 22 mice given the Noni, survived for more than 50 days. This is a life span more than 4 times greater than the longest living mouse not receiving the Noni. This an incredible achievement! Now remember, these were not just any mice, these mice were specifically bred to succumb to this form of cancer. In this regard, they were "genetically doomed" to be cancer victims. Yet in spite of this, a simple Noni extract gave these mice as much as 4 times the life span of their untreated relatives.
HOW NONI DID IT
I know you are as excited about what you just read as I am, but the best part may be how the Noni made this incredible achievement possible! Most people would just assume something in the Noni had killed the cancer cells. But like all good scientists, the researchers at the University of Hawaii School of Medicine wanted to know exactly how Noni had accomplished its miracle. What they found was quite surprising, and very important. They discovered that there was nothing in their Noni extract that killed the cancer cells. What they discovered was that there was a polysaccharide compound (6-D-glucopyranose pentaacetate) found in the Noni that INCREASED THE ABILITY OF THE IMMUNE SYSTEM TO PRODUCE CHEMICALS THAT ENHANCED THE KILLING POWER OF THE WHITE BLOOD CELLS.
Do you realize the great significance of that discovery? You see white blood cells have to kill many things besides cancer cells. They have to defend us against virus, bacteria, yeast, ameba, parasites and all types of invaders. Since this Noni polysaccharide worked by increasing the overall killing power of the white blood cells, this means it will most likely enhance that same killing power against any invader. It indicates Noni is very likely an overall immune enhancing substance that may provide that little extra which gives you the winning edge when some invading organism attacks your body.
MORE CANCER FIGHTING POWER IS FOUND
Japanese scientists were looking for a substance to fight cancer. They searched through over 500 different extracts from tropical plants looking for something which would inhibit the growth of RAS cancer cells. These are a particular type of fast growing and very malignant cancer cells that are hard to stop. Reporting in the journal Cancer Letters, the scientists stated that the Noni extract was by far the most effective at inhibiting and normalizing RAS transformed cancer cells. RAS is a normal part of the cell structure in every cell. It is a small protein which is part of the RNA of the cell and encodes for the reproduction of the cell. Only when it is activated by a carcinogenic protein within the cell does it trigger the cells to reproduce wildly. If you can turn off this uncontrolled RAS activity, you stop the cancers growth.8, 9. What the Japanese scientists found was that one of the phytochemicals in the Noni extract does exactly that! They found that it was the phytochemical in the Noni extract which goes by the fancy name of Damnacanthal that does this. When they added the Noni extract to RAS activated cancer cells they observed them daily for five days. What they saw was incredible!
They reported that slowly, day by day the cells began to change their morphology (cell structure) back to normal. It is only on the basis of this kind of hard science that doctors can rely upon the ability of a plant extract to produce the return to good health now being seen clinically by people who have been struggling with cancer. No one knows if Noni will produce a return to good health for any specific person, but the research shows there is a scientific basis for believing that it is possible. The above represent only a sample of the research completed on the Morinda citrifolia plant. The results are conclusive in each case in showing the validity of the traditional use of the Noni.
REFERENCES CITED IN THE TEXT
1. Limehouse,DVM, John B., Letter publicly circulated, dated February 6, 1997
2. Hall, M.D., Steven M., Statement publicly circulated, dated January 7, 1997
3. Phytochemicals, 1994, Newsweek Magazine, April 25
4. Duke, PhD, James A., Handbook of Phytochemicals, Published by CRC Publishing, Boca Raton, Fl.
6. Hirazumi, A, et al, 1994, Proceedings Western Pharmacology Society, 37: 145-146
7. Hirazumi, A., et al, 1996, Proceedings Western Pharmacology Society, 39: 7 - 9
8. Sylvester, Edward, J., 1986, Target Cancer, Charles Scribner's Sons,N.Y., 9. Fackelman, K., 1997, Science News, 151: 274-275
9. Hiramatsu, M, et al, 1993, Cancer Letters, 73: 161-66
10. Lanettia, 1997, Carbohydrate Antigen 19- 9 Lab Report, SmithKline Beecham Clinical Laboratories
11. Consuela, 1997, Carbohydrate Anitgen 19- 9 Lab Results, Private Communication
12. Levland, 0, & Larson, H.O., 1979, Some Chemical Constituants of Morinda Citrifolia (Noni), Planta Medica, 36: 186 -87
13. Koumaglo, K., et al, 1992, Planta Medica, 58: 6
14. Younos, C et al, 1990, Planta Medica, 56: 5
15. Heinicke, Ralph, M., 1985, Bulletin National Tropical Garden, Hawaii
No commercial company makes any medical claims and is not associated with the contents of this document in any way. This document is a compilation of information gathered from the listed and other sources and is provided here for your education only. It is in no way meant to be taken as medical advice or be used as a substitution for any medical treatment. Consult your physician with any questions.