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enzimnoni-mengkudu | 4:07 AM |
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Sunday, September 4, 2011
enzimnoni-mengkudu | 8:52 PM |
- Anti-inflammation – Researchers from the University of Hawaii found Noni fruit juice to have inflammation-reducing constituents and the ability to suppress the COX-2 enzyme responsible for inflammation and pain.*
- The immune system – Noni juice is a powerful natural food supplement to add to your diet because of its ability to stimulate your immune system into action. By drinking Noni juice daily, your body’s immune system is optimized to respond against the invasion of outside bacteria, germs and viruses as it fights them off and protects you from infection*.
- The circulatory and cardiovascular systems – Noni fruit juice contains scopoletin, which has been shown to lower high-blood pressure by dilating constricted blood vessels. Noni also stimulates the body to produce nitric oxide and it relaxes and expands blood vessels, alleviating stress on the arteries and the heart providing valuable benefits for improved health*.
- The digestive tract – Noni aids the digestive enzymes to efficiently break down food more thoroughly to absorb nutrients taken into the body from the foods eaten*.
- Emotional and mental well-being – Noni is believed to boost serotonin in the brain that has been shown to aid in clearer thinking, better focus and concentration and an elevation in mood and sense of well-being*.
An in-depth study of Noni juice and it's medicinal health benefits was conducted by Johns Hopkins trained Physician Dr. Neil Solomon who gathered from more than 1,227 health professionals representing over 25,314 noni juice drinkers from over 80 countries who received positive results by drinking Noni juice. His researched focused on TAHITIAN NONI™ juice because at the time of his study had the largest known base of Noni juice consumers.We can only wonder how much higher the "% Helped" in his research would have been if he sampled people who drank 100% pure NONI juice, rather than a reconstituted Noni juice blend containing only 89% Noni fruit juice, supplemented with other fruit concentrate fillers. We present his findings here for educational purposes. Every time something new comes along in the health food scene, there’s a huge buzz around the product with plenty of people opting for it and other’s condemning it as mere hype. It’s been the same with noni juice, which has become popular for those who are conscious about their health.
Noni juice is derived from the noni fruit, also known as the Great Morinda. This fruit is found in abundance in the Polynesian islands, Southeast Asia as well as Australia, but it’s juice is indeed a worthy discovery, one that has bettered the lives of many people. Scientists are constantly corroborating newer findings about noni with clinical studies and in depth research. As a result of the hype around noni juice, many people have tried to cash in on it and this has caused quite a few people to regard it as a high level MLM scam. However, this is not the case everywhere. Remember that there are people who have benefited from noni juice.
Actually, the way in which noni juice is processed is of prime importance. This is because it loses its efficacy if too much heat is used, or if it is diluted. Some producers of noni juice use artificial sweeteners because noni juice has a strong taste and smell and is not palatable. Some even use preservatives that does more harm than good. So before you go out to buy your dose of noni juice, look out for the way in which it has been processed. Fresh noni is a richer source of nutrients than bottled juice, so keep that in mind before you buy your noni juice.
Finally, why should you drink noni juice? How can it benefit you?
- Noni juice is known to be rich in phytochemicals that can help in prevention of diseases such as cancer, diabetes, heart diseases, Alzheimer’s etc.
- Noni juice can also help in improving mood and inducing sleep in those suffering from sleep related disorders.
- Better skin, better hair and fewer allergy related reactions are what some of the users of noni juice are claiming.
- Noni juice is known to have many therapeutic effects – antiviral, antibacterial, antifungal, anti-inflammatory, you name it, it does it!
- Some people consume noni juice to correct premature aging and build better bone strength.
- One of the fewer known applications of noni juice is that it has been known to alleviate burns. Freshly squeezed noni juice applied directly can help in healing burns to a great extent.
- Noni juice has a few more external applications also. When rubbed on the skin, it can help reduce skin conditions such as eczema or ringworm. It can be used as a poultice and a compress as well. Some people even rub noni juice on their scalp for lustrous hair and better scalp health.
Most often you will find that the noni juice that you get in most health stores is reconstituted and not the real thing. There are some brands which give it to you as it comes and so, they can be a little hard to stomach because of their strong taste. What’s important is that it has all the goodness you need. Concentrated noni juice has all these benefits, although you might want to know about some of the side effects as well. Noni juice when consumed regularly brings about a detoxification process in your body that may lead to a few side effects such as appearance of boils and pimples, foul breath, diarrhea or gas, headaches and joint pain. While these do sound discomfiting, they are apparently only a way for your body to get rid of all the toxins. Drinking plenty of water will help in flushing out those toxins more easily.
While there are many variants in the market, you might wonder if acquiring pure noni juice is difficult because of the price. Yes, pure noni juice is obviously priced higher because of the effort and time taken in processing it in the right manner. But irrespective of the price, here are a few tips to ascertain whether the noni juice you have is good or not.
- Bubbles – Shake the bottle to see if bubbles form. If the bubbles dissipate quickly, it means that there’s a higher concentration of water than noni juice in it.
- Color – When you shake the bottle, see if the color of the bubbles is brownish. This indicates purity.
- Residue – Good noni juice always has plenty of residue at the bottom. Turn the bottle upside down and note how much residue is visible.
- Taste and smell – Finally, observe the taste and smell of the noni juice. Noni is strong smelling stuff and it is definitely an acquired taste. If it has been flavored with other fruit juices, it might not be pure.
Thursday, May 26, 2011
enzimnoni-mengkudu | 3:17 AM |
Noni juice has benefited the people of the South Pacific Islands for the past 2,000 years to aid a wide-range of health conditions to include: immune problems, joint pain, infection, colds, digestive disorders, injuries and inflammation.*Clinical researchers have identified well over 150 nutraceuticals in Noni fruit juice that have therapeutic value in the human body. Fresh-pressed Noni juice includes a potent mixture of nature’s most powerful phytonutrients and antioxidant that actively neutralize cell-damaging “free radicals” created in your body.
Top 5 Health Benefits Derived from NONI Juice:
1. Anti-inflammation – Researchers from the University of Hawaii found Noni fruit juice to have inflammation-reducing constituents and the ability to suppress the COX-2 enzyme responsible for inflammation and pain.*
2. The immune system – Noni juice is a powerful natural food supplement to add to your diet because of its ability to stimulate your immune system into action. By drinking Noni juice daily, your body’s immune system is optimized to respond against the invasion of outside bacteria, germs and viruses as it fights them off and protects you from infection*.
3. The circulatory and cardiovascular systems – Noni fruit juice contains scopoletin, which has been shown to lower high-blood pressure by dilating constricted blood vessels. Noni also stimulates the body to produce nitric oxide and it relaxes and expands blood vessels, alleviating stress on the arteries and the heart providing valuable benefits for improved health*.
4. The digestive tract – Noni aids the digestive enzymes to efficiently break down food more thoroughly to absorb nutrients taken into the body from the foods eaten*.
5. Emotional and mental well-being – Noni is believed to boost serotonin in the brain that has been shown to aid in clearer thinking, better focus and concentration and an elevation in mood and sense of well-being*.
25,00 noni juice drinkers
An in-depth study of Noni juice and it's medicinal health benefits was conducted
by Johns Hopkins trained Physician Dr. Neil Solomon who gathered from more than
1,227 health professionals representing over 25,314 noni juice drinkers from over
80 countries who received positive results by drinking Noni juice. His researched
focused on TAHITIAN NONI™ juice because at the time of his study had the
largest known base of Noni juice consumers.We can only wonder how much
higher the "% Helped" in his research would have been if he sampled people
who drank 100% pure NONI juice, rather than a reconstituted Noni juice
blend containing only 89% Noni fruit juice, supplemented with other fruit
concentrate fillers. We present his findings here for educational purposes.
Editions, Decreased Symptoms Total # %Helped
1. Allergy 3,198 86%
2. Arthritis 1,675 78%
3. Asthma 8,077 71%
4. Cancer 2,188 69%
. CFIDS, Fibromyalgia 3,524 77%
6. Depression 1,512 80%
7. Diabetics, Types 1 & 2 5,575 82%
8. Digestion 3,171 90%
9. Energy, increased 16,056 90%
10. Heart Disease 2,158 76%
11. High Blood Pressure, decreased 1,869 84%
12. HIV 150 55%
13. Immune System 3,707 77%
14. Kidney Disease 3,764 67%
15. Menstruation 3,798 79%
16. Mental Acuity, increased alertness 5,543 73%
17. Multiple Sclerosis 25
18. Muscle, increased body building 1,216 70%
19. Obesity, lost some excess weight 5,526 72%
20. Pain, including headaches 6,828 86%
21. Parkinson's Disease 25 52%
22. Respiratory Problems 3,857 72%
23. Skin and Hair Problems 877 78%
24. Sexual Enhancement increased 2,984 84%
25. Sleep, improved 2,025 75%
26. Smoking, stopped 876 56%
27. Stress, coped better 6,743 74%
28. Stroke 1,806 53%
29. Well-being, felt better 7,879 80%
Medical Benefits of Noni Juice
Noni is a type of mulberry that produces a pungent, bitter juice packed with vitamins, minerals, amino acids and antioxidants. The popularity of this juice has risen in the last two decades, but has been used for centuries in some South Pacific and Asian countries. This juice offers numerous health benefits, does not interact with medications and has no known side effects.
Top 5 Health Benefits Derived from NONI Juice:
1. Anti-inflammation – Researchers from the University of Hawaii found Noni fruit juice to have inflammation-reducing constituents and the ability to suppress the COX-2 enzyme responsible for inflammation and pain.*
2. The immune system – Noni juice is a powerful natural food supplement to add to your diet because of its ability to stimulate your immune system into action. By drinking Noni juice daily, your body’s immune system is optimized to respond against the invasion of outside bacteria, germs and viruses as it fights them off and protects you from infection*.
3. The circulatory and cardiovascular systems – Noni fruit juice contains scopoletin, which has been shown to lower high-blood pressure by dilating constricted blood vessels. Noni also stimulates the body to produce nitric oxide and it relaxes and expands blood vessels, alleviating stress on the arteries and the heart providing valuable benefits for improved health*.
4. The digestive tract – Noni aids the digestive enzymes to efficiently break down food more thoroughly to absorb nutrients taken into the body from the foods eaten*.
5. Emotional and mental well-being – Noni is believed to boost serotonin in the brain that has been shown to aid in clearer thinking, better focus and concentration and an elevation in mood and sense of well-being*.
25,00 noni juice drinkers
An in-depth study of Noni juice and it's medicinal health benefits was conducted
by Johns Hopkins trained Physician Dr. Neil Solomon who gathered from more than
1,227 health professionals representing over 25,314 noni juice drinkers from over
80 countries who received positive results by drinking Noni juice. His researched
focused on TAHITIAN NONI™ juice because at the time of his study had the
largest known base of Noni juice consumers.We can only wonder how much
higher the "% Helped" in his research would have been if he sampled people
who drank 100% pure NONI juice, rather than a reconstituted Noni juice
blend containing only 89% Noni fruit juice, supplemented with other fruit
concentrate fillers. We present his findings here for educational purposes.
Editions, Decreased Symptoms Total # %Helped
1. Allergy 3,198 86%
2. Arthritis 1,675 78%
3. Asthma 8,077 71%
4. Cancer 2,188 69%
. CFIDS, Fibromyalgia 3,524 77%
6. Depression 1,512 80%
7. Diabetics, Types 1 & 2 5,575 82%
8. Digestion 3,171 90%
9. Energy, increased 16,056 90%
10. Heart Disease 2,158 76%
11. High Blood Pressure, decreased 1,869 84%
12. HIV 150 55%
13. Immune System 3,707 77%
14. Kidney Disease 3,764 67%
15. Menstruation 3,798 79%
16. Mental Acuity, increased alertness 5,543 73%
17. Multiple Sclerosis 25
18. Muscle, increased body building 1,216 70%
19. Obesity, lost some excess weight 5,526 72%
20. Pain, including headaches 6,828 86%
21. Parkinson's Disease 25 52%
22. Respiratory Problems 3,857 72%
23. Skin and Hair Problems 877 78%
24. Sexual Enhancement increased 2,984 84%
25. Sleep, improved 2,025 75%
26. Smoking, stopped 876 56%
27. Stress, coped better 6,743 74%
28. Stroke 1,806 53%
29. Well-being, felt better 7,879 80%
Medical Benefits of Noni Juice
Noni is a type of mulberry that produces a pungent, bitter juice packed with vitamins, minerals, amino acids and antioxidants. The popularity of this juice has risen in the last two decades, but has been used for centuries in some South Pacific and Asian countries. This juice offers numerous health benefits, does not interact with medications and has no known side effects.Vitamins, Minerals and Amino Acids
- Noni juice contains vitamins A and C, niacin and calcium. It also has a high amount of potassium. For this reason, the Mayo Clinic recommends that individuals use caution if they have a kidney disease or are taking potassium-sparing diuretics, angiotensin-converting enzyme inhibitors or angiotension II receptor blockers, as they may make the potassium levels in the body rise to a dangerous level.
Pain Reducer
- Noni acts as an anti-inflammatory agent to reduce pain associated with arthritis and joint discomfort. Noni also protects the kidneys, liver and stomach as it works, which is something that many pharmaceutical pain relievers do not offer.
Pineal Gland Stimulation
- The pineal gland helps regulate several glands throughout the body. If the pineal gland is not functioning properly, the other glands may also have the same effect. The pineal gland produces melanin, a helpful pigment that is found throughout the body. Noni juice stimulates the production of this pigment within the pineal gland.
Digestive Functioning
- Digestive functioning shows improvement after taking noni juice. The juice helps to clean and remove unwanted parasites from the digestive tract. Individuals that suffer from ulcers, constipation, diarrhea, food poisoning and irritable bowel syndrome may benefit from taking Noni.
Antioxidant Benefits
- Noni juice is a powerful antioxidant that helps rid the body of free radicals. Free radicals are particles that are formed when weak bonds of molecules in the body break apart and are released into the body. These free radicals are unstable by nature and attack nearby cells in efforts to balance themselves out. This can cause damage to various cells throughout the body and DNA. Noni juice helps balance the free radicals by giving them the molecular stability they need to cease this damaging behavior.
Alkalinity Balancing
- Noni helps balance out the alkalinity within the body. Diseases flourish and tissues can get damaged in an environment that is too acidic.
Blood Sugar Regulation
- Noni aids the pancreas in regulating and stabilizing blood sugar levels. This is beneficial for people who suffer from diabetes and hypoglycemia.
Macular Generation
- The macular is located in the back side of the eye and contains a pigment called melanin. If this pigment is lost, this is called macular degeneration and results in blindness. Noni helps add more pigment to this area, resulting in the regeneration of cells which helps reverse the condition.
Uterus Health
Women that are experiencing fibroids in the uterus have reported reduction of symptoms after drinking noni juice. Other women have reported that their menstruation cycle normalizes and produces less crampingNoni Juice Pros & Cons
Noni juice has grown in popularity, and many distributors have begun producing it. Purists believe the best noni juice comes from the pollutant-free volcanic soils of the South Pacific. The harvesting of the noni fruit is imperative in maintaining the healthiest benefits.
History
- The Polynesians first discovered the medical uses of noni juice more than 2,000 years ago. In 2003, the European Commission approved noni juice as a novel food and allowed it to be commercialized. New foods in Europe are stringently tested for safety.
Uses
- Noni juice is used for those with arthritis, immune disorders, colds, cancer, depression, hypertension, high blood pressure, skin infections and pain. It contains antibacterial compounds that help guard against infections and diseases.
Vitamins
- Noni juice is rich in vitamin A, calcium, sodium, vitamin C, niacin and potassium. It also contains 10 essential vitamins, seven dietary mineral and 18 amino acids. Noni juice contains xeronine, an alkaloid needed for proper cell function.
Side Effects
- Like other natural products, noni juice does have some side effects. These include coughing, headaches, bloating, gas, diarrhea, joint pain, foul breath, rashes, fatigue and heavy periods in women.
Considerations
Most of these side effects are short-lived and occurred in less than 10 percent of those who consumed the juice. Also, those experiencing side effects might have had an allergic reaction to the fruit.Warnings
- Noni juice typically has an unpleasant taste when it isn't flavored with additives. Those looking for nutritional benefits may prefer to look to other more palatable fruit juices or pursue the type of noni juice with flavor additives.
Noni juice can be high in potassium, which can prove dangerous for those with kidney disease, as it can cause potassium levels in the blood to get dangerously high, a condition called hyperkalemia.
Tuesday, October 26, 2010
enzimnoni-mengkudu | 2:20 AM |
Dr. Ralph Heinicke pioneered the study of the alkaloid Xeronine. Xeronine is produce in the body from the building blocks Proxeronine and Proxeronase. These building blocks are abundant in the juice of the Morinda citrifolia fruit.
Xeronine is a relatively small alkaloid that is physiologically active in the picogram range. (Editorial note: a picogram is one trillionth of a gram.) It occurs in practically all healthy cells of plants, animals and microorganisms. However, the amount of free alkaloid is minute, and is well below the limits of normal chemical analytical techniques.
How Fed Noni Enzyme Can Fight The Cancer?
Main components was found in Noni that can reestablish body cell to fight cancer is Xeronine. It is also call "dry alkaline compound" which is found in found in green fruit. One of them is noni fruit.
Fed Noni is 100% pure natural noni enzyme and based on survey conducted by Dr Neil Solomon to about 886 people where 50 are doctor and the rest are cancer patient respondent, the result show about 65% of them give positive feedback and very effective result. Cancer patient are among prostate, breast, colon cancer and etc. Study or survey was done in 1999.
1. XERONINE
As a researcher in Hawaii, Dr. Ralph Heinicke became aware of the marvelous benefits of the Noni fruit and set out to find the pharmacologically active ingredient of the Noni. Dr. Heinicke had spent over 45 years studying the effects of an alkaloid he discovered and named xeronine.
Xeronine is a relatively small alkaloid which is physiologically very active and important for the proper functioning of all cells in the body. In his research, Dr. Heinicke discovered that the Noni juice contains appreciable amounts of the precursor of xeronine that he named "proxeronine". "Proxeronine" releases pure xeronine in the intestines when it comes in contact with a particular enzyme also found in the Noni Juice.
Dr. Heinicke's theory is that, when released, xeronine actually works at the molecular level to repair damaged cells. Dr. Heinicke states that the primary function of xeronine is to regulate the rigidity and shape of specific proteins. Since these proteins have different functions within the cells, this explains how the administration of Noni Juice causes an unbelievably wide range of physiological responses. "Some of the problems which drinking Noni Juice might favorably affect are: high blood pressure, menstrual cramps, arthritis, gastric ulcers, sprains, injuries, mental depression, senility, poor digestion, atherosclerosis, blood vessel problems, drug addiction, relief of pain, and many others. Although this list looks like a page torn out of a traveling medicine man's manual, it is probably conservative." - Dr. Heinicke
When Ralph M. Heinicke received his doctorate in biochemistry from the University of Minnesota, he wanted to escape from those cold Minnesota winters and so he took a job with Dole Pineapple Company in Hawaii. His first assignment was to develop a method to extract the enzyme that caused pineapple to prevent gelatin deserts from setting up. He found it was an enzyme called bromelain and in due time he and his coworkers found a way to extract it. Soon the Dole Company found that every day they had over a thousand pounds of this crude bromelain enzyme extract left over as a waste product. At the time it had no commercial value, and so the company president asked Dr. Heinicke to see if he could find some use for this material. Eventually he found it was a proteolytic enzyme that had some medical applications. He worked with Smith-Kline and the Rohr pharmaceutical companies to expand its medical use.
In order to get FDA approval for this enzyme he had to refine the crude bromelain extract down to an extremely pure protease enzyme. Much to his and the drug companies amazement, the more pure the enzyme became, the less beneficial it was in many of its applications. Eventually, in its purest state, it had only 5% of its original potency for many of its uses. Dr. Heinicke was then asked to find what it was they were removing that had given the crude bromelain extract all of its power. Meanwhile the giant Japanese drug company Toshiba had also launched a 3 year, 3 million dollar program to find the same answer. At the end of that time they had used up all their money and not found the answer. Not one to give up easily, Dr. Heinicke continued his research and eventually found to his great surprise that the active ingredient was not a protein, carbohydrate or fat, but a substance known as an alkaloid.
Alkaloids are one of the most important classes of phytochemicals known, and are a major source from which many modern medicines are drawn from Nature. By isolating this alkaloid into a pure state, he was able to identify is exact chemical structure. Because it could be reduced to a dry crystalline structure he decided to use the latin prefix "Xero" meaning "dry" as the first part of its name. Since it was also an alkaline compound he tacked on the suffix "ine" indicating its alkaline nature. When the prefix and suffix are combined it gives us the word "Xeronine" which means, "a dry alkaline compound". Which is the descriptive name he chose for the compound he discovered.
Eventually he found that Xeronine was a very important biochemical in the human body and essential for good health. So essential that the human body has a limited ability to manufacture it from the raw material found in certain fruits. Like many other biochemicals produced in the body, he found that positive thoughts and emotions, along with exposure to art, music, nature and spiritual experiences increased its production. While negative thoughts, emotions and stressful experiences suppressed it's production. He also learned that as the body's level of Xeronine declined with age, stress and a poor diet, the level of health and recovery declined right along with it.
2. PHYTOCHEMICAL
PHYTOCHEMICALS REVERSE CANCER
The power of phytochemicals to promote good health and control cancer is so impressive that the University of Illinois has created a whole new department with 63 scientists and professors to specialize in phytochemical research! Let me share with you some of the scientific findings leading to this major change in research.
Senior Science Advisor to the U.S. Public Health Service, Dr. D.L. Davis states, "Phytochemicals can take tumors and defuse them. They can turn off the proliferative process of cancer." At Ohio State University's Cancer Prevention Laboratory, Dr. Mark Morse and colleagues found that phytochemicals in broccoli known as sulforaphane could reduce esophageal tumor incidence by as much as 40% and reduce the multiplication of such cancer cells by 90%. Dr. Paul Taladay working at John Hopkins Medical Institute has found that this same phytochemical protected animals from getting cancer even when exposed to cancer causing chemicals. According to Dr. Joseph Hotchkiss of Cornell University, University, the phytochemicals coumaric acid and chlorogenic acid are able to eliminate many cancer causing substances from the body. An epidemiologist at the University of Minnesota, Dr. John Potter, told Newsweek Magazine, "At almost every step along the pathway to cancer, phytochemicals slow up or reverse the process." Most of these phytochemicals studied so far are found in ordinary vegetables and culinary herbs. The problem is the amount in these foods is so low that only if you eat a lot of them for a long time will they give you protection. If you already have cancer, what you need is a plant that has these phytochemicals in large enough amounts to go right to work.
NONI IS A TREASURE CHEST OF PHYTOCHEMICALS
When plant scientists at the U.S. Department of Agriculture studied the amazing Noni plant they quickly found the secret to its amazing health building power. It is endowed with a greater number and variety of health giving phytochemicals than just about any plant known. Dr. James A. Duke is one of the world's most highly respected scientific authorities on herbs and their phytochemical content. In his authoritative CRC Handbook on Phytochemicals he has listed 23 different phytochemicals found in Noni as well as 5 vitamins and 3 minerals. Research on Noni continues at an ever increasing pace with more of its phytochemicals being uncovered all the time.
IT IS THE INCREDIBLE POWER OF THESE PHYTOCHEMICALS THAT ARE PRODUCING THE WONDERFUL HEALTH BUILDING RESULTS DOCTORS AND PATIENTS ARE NOW SEEING AS A RESULT OF USING THIS AMAZING FRUIT! AS SAFE TO USE AS ANY FRUIT ON THE MARKET
The U.S. Food and Drug Administration, as well as the Department of Agriculture maintain a list of plants that have no known harmful ingredients and which over the test of time with large numbers of people have proven themselves to be safe for human consumption by the general population. This is known as the GRAS list, and it stands for Generally Recognized As Safe. Based on the fact that after careful scientific analysis no harmful ingredients were found, and the Polynesian people have been using this health building herb without harm for thousands of years, NONI HAS BEEN OFFICIALLY DESIGNATED AS GENERALLY RECOGNIZED AS SAFE.
Even though Noni is extremely safe, I would always suggest that the introduction of a new herb into the diet be approached with caution by anyone known to have food sensitivities, allergies, or asthma. I would also caution a woman who is pregnant or nursing to consult her physician before using Noni or any other herb.
HOW NONI HELPS THE BODY FIGHT OFF CANCER
Researchers at the University of Hawaii School of Medicine introduced cells containing a strain of lung cancer known as Lewis Lung Carcinoma into a group of mice especially bred to be highly susceptible to this type of cancer. Within 9 to 12 days the mice which were given no Noni were all dead as a result of the growth of the tumor. However, another group of these same mice were given an extract of the Noni fruit on five different occasions. At the end of the 12 days when all the untreated mice were dead, those given the Noni were still alive and doing well! At the end of 24 days, the Noni treated mice were all still going strong, this was a 100% extension of life! Actually, 40% which is 9 out of the 22 mice given the Noni, survived for more than 50 days. This is a life span more than 4 times greater than the longest living mouse not receiving the Noni. This an incredible achievement! Now remember, these were not just any mice, these mice were specifically bred to succumb to this form of cancer. In this regard, they were "genetically doomed" to be cancer victims. Yet in spite of this, a simple Noni extract gave these mice as much as 4 times the life span of their untreated relatives.
HOW NONI DID IT
I know you are as excited about what you just read as I am, but the best part may be how the Noni made this incredible achievement possible! Most people would just assume something in the Noni had killed the cancer cells. But like all good scientists, the researchers at the University of Hawaii School of Medicine wanted to know exactly how Noni had accomplished its miracle. What they found was quite surprising, and very important. They discovered that there was nothing in their Noni extract that killed the cancer cells. What they discovered was that there was a polysaccharide compound (6-D-glucopyranose pentaacetate) found in the Noni that INCREASED THE ABILITY OF THE IMMUNE SYSTEM TO PRODUCE CHEMICALS THAT ENHANCED THE KILLING POWER OF THE WHITE BLOOD CELLS.
Do you realize the great significance of that discovery? You see white blood cells have to kill many things besides cancer cells. They have to defend us against virus, bacteria, yeast, ameba, parasites and all types of invaders. Since this Noni polysaccharide worked by increasing the overall killing power of the white blood cells, this means it will most likely enhance that same killing power against any invader. It indicates Noni is very likely an overall immune enhancing substance that may provide that little extra which gives you the winning edge when some invading organism attacks your body.
MORE CANCER FIGHTING POWER IS FOUND
Japanese scientists were looking for a substance to fight cancer. They searched through over 500 different extracts from tropical plants looking for something which would inhibit the growth of RAS cancer cells. These are a particular type of fast growing and very malignant cancer cells that are hard to stop. Reporting in the journal Cancer Letters, the scientists stated that the Noni extract was by far the most effective at inhibiting and normalizing RAS transformed cancer cells. RAS is a normal part of the cell structure in every cell. It is a small protein which is part of the RNA of the cell and encodes for the reproduction of the cell. Only when it is activated by a carcinogenic protein within the cell does it trigger the cells to reproduce wildly. If you can turn off this uncontrolled RAS activity, you stop the cancers growth.8, 9. What the Japanese scientists found was that one of the phytochemicals in the Noni extract does exactly that! They found that it was the phytochemical in the Noni extract which goes by the fancy name of Damnacanthal that does this. When they added the Noni extract to RAS activated cancer cells they observed them daily for five days. What they saw was incredible!
They reported that slowly, day by day the cells began to change their morphology (cell structure) back to normal. It is only on the basis of this kind of hard science that doctors can rely upon the ability of a plant extract to produce the return to good health now being seen clinically by people who have been struggling with cancer. No one knows if Noni will produce a return to good health for any specific person, but the research shows there is a scientific basis for believing that it is possible. The above represent only a sample of the research completed on the Morinda citrifolia plant. The results are conclusive in each case in showing the validity of the traditional use of the Noni.
Xeronine is a relatively small alkaloid that is physiologically active in the picogram range. (Editorial note: a picogram is one trillionth of a gram.) It occurs in practically all healthy cells of plants, animals and microorganisms. However, the amount of free alkaloid is minute, and is well below the limits of normal chemical analytical techniques.
How Fed Noni Enzyme Can Fight The Cancer?
Main components was found in Noni that can reestablish body cell to fight cancer is Xeronine. It is also call "dry alkaline compound" which is found in found in green fruit. One of them is noni fruit.
Fed Noni is 100% pure natural noni enzyme and based on survey conducted by Dr Neil Solomon to about 886 people where 50 are doctor and the rest are cancer patient respondent, the result show about 65% of them give positive feedback and very effective result. Cancer patient are among prostate, breast, colon cancer and etc. Study or survey was done in 1999.
1. XERONINE
As a researcher in Hawaii, Dr. Ralph Heinicke became aware of the marvelous benefits of the Noni fruit and set out to find the pharmacologically active ingredient of the Noni. Dr. Heinicke had spent over 45 years studying the effects of an alkaloid he discovered and named xeronine.
Xeronine is a relatively small alkaloid which is physiologically very active and important for the proper functioning of all cells in the body. In his research, Dr. Heinicke discovered that the Noni juice contains appreciable amounts of the precursor of xeronine that he named "proxeronine". "Proxeronine" releases pure xeronine in the intestines when it comes in contact with a particular enzyme also found in the Noni Juice.
Dr. Heinicke's theory is that, when released, xeronine actually works at the molecular level to repair damaged cells. Dr. Heinicke states that the primary function of xeronine is to regulate the rigidity and shape of specific proteins. Since these proteins have different functions within the cells, this explains how the administration of Noni Juice causes an unbelievably wide range of physiological responses. "Some of the problems which drinking Noni Juice might favorably affect are: high blood pressure, menstrual cramps, arthritis, gastric ulcers, sprains, injuries, mental depression, senility, poor digestion, atherosclerosis, blood vessel problems, drug addiction, relief of pain, and many others. Although this list looks like a page torn out of a traveling medicine man's manual, it is probably conservative." - Dr. Heinicke
When Ralph M. Heinicke received his doctorate in biochemistry from the University of Minnesota, he wanted to escape from those cold Minnesota winters and so he took a job with Dole Pineapple Company in Hawaii. His first assignment was to develop a method to extract the enzyme that caused pineapple to prevent gelatin deserts from setting up. He found it was an enzyme called bromelain and in due time he and his coworkers found a way to extract it. Soon the Dole Company found that every day they had over a thousand pounds of this crude bromelain enzyme extract left over as a waste product. At the time it had no commercial value, and so the company president asked Dr. Heinicke to see if he could find some use for this material. Eventually he found it was a proteolytic enzyme that had some medical applications. He worked with Smith-Kline and the Rohr pharmaceutical companies to expand its medical use.
In order to get FDA approval for this enzyme he had to refine the crude bromelain extract down to an extremely pure protease enzyme. Much to his and the drug companies amazement, the more pure the enzyme became, the less beneficial it was in many of its applications. Eventually, in its purest state, it had only 5% of its original potency for many of its uses. Dr. Heinicke was then asked to find what it was they were removing that had given the crude bromelain extract all of its power. Meanwhile the giant Japanese drug company Toshiba had also launched a 3 year, 3 million dollar program to find the same answer. At the end of that time they had used up all their money and not found the answer. Not one to give up easily, Dr. Heinicke continued his research and eventually found to his great surprise that the active ingredient was not a protein, carbohydrate or fat, but a substance known as an alkaloid.
Alkaloids are one of the most important classes of phytochemicals known, and are a major source from which many modern medicines are drawn from Nature. By isolating this alkaloid into a pure state, he was able to identify is exact chemical structure. Because it could be reduced to a dry crystalline structure he decided to use the latin prefix "Xero" meaning "dry" as the first part of its name. Since it was also an alkaline compound he tacked on the suffix "ine" indicating its alkaline nature. When the prefix and suffix are combined it gives us the word "Xeronine" which means, "a dry alkaline compound". Which is the descriptive name he chose for the compound he discovered.
Eventually he found that Xeronine was a very important biochemical in the human body and essential for good health. So essential that the human body has a limited ability to manufacture it from the raw material found in certain fruits. Like many other biochemicals produced in the body, he found that positive thoughts and emotions, along with exposure to art, music, nature and spiritual experiences increased its production. While negative thoughts, emotions and stressful experiences suppressed it's production. He also learned that as the body's level of Xeronine declined with age, stress and a poor diet, the level of health and recovery declined right along with it.
2. PHYTOCHEMICAL
PHYTOCHEMICALS REVERSE CANCER
The power of phytochemicals to promote good health and control cancer is so impressive that the University of Illinois has created a whole new department with 63 scientists and professors to specialize in phytochemical research! Let me share with you some of the scientific findings leading to this major change in research.
Senior Science Advisor to the U.S. Public Health Service, Dr. D.L. Davis states, "Phytochemicals can take tumors and defuse them. They can turn off the proliferative process of cancer." At Ohio State University's Cancer Prevention Laboratory, Dr. Mark Morse and colleagues found that phytochemicals in broccoli known as sulforaphane could reduce esophageal tumor incidence by as much as 40% and reduce the multiplication of such cancer cells by 90%. Dr. Paul Taladay working at John Hopkins Medical Institute has found that this same phytochemical protected animals from getting cancer even when exposed to cancer causing chemicals. According to Dr. Joseph Hotchkiss of Cornell University, University, the phytochemicals coumaric acid and chlorogenic acid are able to eliminate many cancer causing substances from the body. An epidemiologist at the University of Minnesota, Dr. John Potter, told Newsweek Magazine, "At almost every step along the pathway to cancer, phytochemicals slow up or reverse the process." Most of these phytochemicals studied so far are found in ordinary vegetables and culinary herbs. The problem is the amount in these foods is so low that only if you eat a lot of them for a long time will they give you protection. If you already have cancer, what you need is a plant that has these phytochemicals in large enough amounts to go right to work.
NONI IS A TREASURE CHEST OF PHYTOCHEMICALS
When plant scientists at the U.S. Department of Agriculture studied the amazing Noni plant they quickly found the secret to its amazing health building power. It is endowed with a greater number and variety of health giving phytochemicals than just about any plant known. Dr. James A. Duke is one of the world's most highly respected scientific authorities on herbs and their phytochemical content. In his authoritative CRC Handbook on Phytochemicals he has listed 23 different phytochemicals found in Noni as well as 5 vitamins and 3 minerals. Research on Noni continues at an ever increasing pace with more of its phytochemicals being uncovered all the time.
IT IS THE INCREDIBLE POWER OF THESE PHYTOCHEMICALS THAT ARE PRODUCING THE WONDERFUL HEALTH BUILDING RESULTS DOCTORS AND PATIENTS ARE NOW SEEING AS A RESULT OF USING THIS AMAZING FRUIT! AS SAFE TO USE AS ANY FRUIT ON THE MARKET
The U.S. Food and Drug Administration, as well as the Department of Agriculture maintain a list of plants that have no known harmful ingredients and which over the test of time with large numbers of people have proven themselves to be safe for human consumption by the general population. This is known as the GRAS list, and it stands for Generally Recognized As Safe. Based on the fact that after careful scientific analysis no harmful ingredients were found, and the Polynesian people have been using this health building herb without harm for thousands of years, NONI HAS BEEN OFFICIALLY DESIGNATED AS GENERALLY RECOGNIZED AS SAFE.
Even though Noni is extremely safe, I would always suggest that the introduction of a new herb into the diet be approached with caution by anyone known to have food sensitivities, allergies, or asthma. I would also caution a woman who is pregnant or nursing to consult her physician before using Noni or any other herb.
HOW NONI HELPS THE BODY FIGHT OFF CANCER
Researchers at the University of Hawaii School of Medicine introduced cells containing a strain of lung cancer known as Lewis Lung Carcinoma into a group of mice especially bred to be highly susceptible to this type of cancer. Within 9 to 12 days the mice which were given no Noni were all dead as a result of the growth of the tumor. However, another group of these same mice were given an extract of the Noni fruit on five different occasions. At the end of the 12 days when all the untreated mice were dead, those given the Noni were still alive and doing well! At the end of 24 days, the Noni treated mice were all still going strong, this was a 100% extension of life! Actually, 40% which is 9 out of the 22 mice given the Noni, survived for more than 50 days. This is a life span more than 4 times greater than the longest living mouse not receiving the Noni. This an incredible achievement! Now remember, these were not just any mice, these mice were specifically bred to succumb to this form of cancer. In this regard, they were "genetically doomed" to be cancer victims. Yet in spite of this, a simple Noni extract gave these mice as much as 4 times the life span of their untreated relatives.
HOW NONI DID IT
I know you are as excited about what you just read as I am, but the best part may be how the Noni made this incredible achievement possible! Most people would just assume something in the Noni had killed the cancer cells. But like all good scientists, the researchers at the University of Hawaii School of Medicine wanted to know exactly how Noni had accomplished its miracle. What they found was quite surprising, and very important. They discovered that there was nothing in their Noni extract that killed the cancer cells. What they discovered was that there was a polysaccharide compound (6-D-glucopyranose pentaacetate) found in the Noni that INCREASED THE ABILITY OF THE IMMUNE SYSTEM TO PRODUCE CHEMICALS THAT ENHANCED THE KILLING POWER OF THE WHITE BLOOD CELLS.
Do you realize the great significance of that discovery? You see white blood cells have to kill many things besides cancer cells. They have to defend us against virus, bacteria, yeast, ameba, parasites and all types of invaders. Since this Noni polysaccharide worked by increasing the overall killing power of the white blood cells, this means it will most likely enhance that same killing power against any invader. It indicates Noni is very likely an overall immune enhancing substance that may provide that little extra which gives you the winning edge when some invading organism attacks your body.
MORE CANCER FIGHTING POWER IS FOUND
Japanese scientists were looking for a substance to fight cancer. They searched through over 500 different extracts from tropical plants looking for something which would inhibit the growth of RAS cancer cells. These are a particular type of fast growing and very malignant cancer cells that are hard to stop. Reporting in the journal Cancer Letters, the scientists stated that the Noni extract was by far the most effective at inhibiting and normalizing RAS transformed cancer cells. RAS is a normal part of the cell structure in every cell. It is a small protein which is part of the RNA of the cell and encodes for the reproduction of the cell. Only when it is activated by a carcinogenic protein within the cell does it trigger the cells to reproduce wildly. If you can turn off this uncontrolled RAS activity, you stop the cancers growth.8, 9. What the Japanese scientists found was that one of the phytochemicals in the Noni extract does exactly that! They found that it was the phytochemical in the Noni extract which goes by the fancy name of Damnacanthal that does this. When they added the Noni extract to RAS activated cancer cells they observed them daily for five days. What they saw was incredible!
They reported that slowly, day by day the cells began to change their morphology (cell structure) back to normal. It is only on the basis of this kind of hard science that doctors can rely upon the ability of a plant extract to produce the return to good health now being seen clinically by people who have been struggling with cancer. No one knows if Noni will produce a return to good health for any specific person, but the research shows there is a scientific basis for believing that it is possible. The above represent only a sample of the research completed on the Morinda citrifolia plant. The results are conclusive in each case in showing the validity of the traditional use of the Noni.
enzimnoni-mengkudu | 2:04 AM |
Noni juice has benefited the people of the South Pacific Islands for the past 2,000 years to aid a wide-range of health conditions to include: immune problems, joint pain, infection, colds, digestive disorders, injuries and inflammation.*Clinical researchers have identified well over 150 nutraceuticals in Noni fruit juice that have therapeutic value in the human body. Fresh-pressed Noni juice includes a potent mixture of nature’s most powerful phytonutrients and antioxidant that actively neutralize cell-damaging “free radicals” created in your body.
Top 5 Health Benefits Derived from NONI Juice:
1. Anti-inflammation – Researchers from the University of Hawaii found Noni fruit juice to have inflammation-reducing constituents and the ability to suppress the COX-2 enzyme responsible for inflammation and pain.*
2. The immune system – Noni juice is a powerful natural food supplement to add to your diet because of its ability to stimulate your immune system into action. By drinking Noni juice daily, your body’s immune system is optimized to respond against the invasion of outside bacteria, germs and viruses as it fights them off and protects you from infection*.
3. The circulatory and cardiovascular systems – Noni fruit juice contains scopoletin, which has been shown to lower high-blood pressure by dilating constricted blood vessels. Noni also stimulates the body to produce nitric oxide and it relaxes and expands blood vessels, alleviating stress on the arteries and the heart providing valuable benefits for improved health*.
4. The digestive tract – Noni aids the digestive enzymes to efficiently break down food more thoroughly to absorb nutrients taken into the body from the foods eaten*.
5. Emotional and mental well-being – Noni is believed to boost serotonin in the brain that has been shown to aid in clearer thinking, better focus and concentration and an elevation in mood and sense of well-being*.
25,00 noni juice drinkers
An in-depth study of Noni juice and it's medicinal health benefits was conducted
by Johns Hopkins trained Physician Dr. Neil Solomon who gathered from more than
1,227 health professionals representing over 25,314 noni juice drinkers from over
80 countries who received positive results by drinking Noni juice. His researched
focused on TAHITIAN NONI™ juice because at the time of his study had the
largest known base of Noni juice consumers.We can only wonder how much
higher the "% Helped" in his research would have been if he sampled people
who drank 100% pure NONI juice, rather than a reconstituted Noni juice
blend containing only 89% Noni fruit juice, supplemented with other fruit
concentrate fillers. We present his findings here for educational purposes.
Editions, Decreased Symptoms Total # %Helped
1. Allergy 3,198 86%
2. Arthritis 1,675 78%
3. Asthma 8,077 71%
4. Cancer 2,188 69%
. CFIDS, Fibromyalgia 3,524 77%
6. Depression 1,512 80%
7. Diabetics, Types 1 & 2 5,575 82%
8. Digestion 3,171 90%
9. Energy, increased 16,056 90%
10. Heart Disease 2,158 76%
11. High Blood Pressure, decreased 1,869 84%
12. HIV 150 55%
13. Immune System 3,707 77%
14. Kidney Disease 3,764 67%
15. Menstruation 3,798 79%
16. Mental Acuity, increased alertness 5,543 73%
17. Multiple Sclerosis 25
18. Muscle, increased body building 1,216 70%
19. Obesity, lost some excess weight 5,526 72%
20. Pain, including headaches 6,828 86%
21. Parkinson's Disease 25 52%
22. Respiratory Problems 3,857 72%
23. Skin and Hair Problems 877 78%
24. Sexual Enhancement increased 2,984 84%
25. Sleep, improved 2,025 75%
26. Smoking, stopped 876 56%
27. Stress, coped better 6,743 74%
28. Stroke 1,806 53%
29. Well-being, felt better 7,879 80%
Top 5 Health Benefits Derived from NONI Juice:
1. Anti-inflammation – Researchers from the University of Hawaii found Noni fruit juice to have inflammation-reducing constituents and the ability to suppress the COX-2 enzyme responsible for inflammation and pain.*
2. The immune system – Noni juice is a powerful natural food supplement to add to your diet because of its ability to stimulate your immune system into action. By drinking Noni juice daily, your body’s immune system is optimized to respond against the invasion of outside bacteria, germs and viruses as it fights them off and protects you from infection*.
3. The circulatory and cardiovascular systems – Noni fruit juice contains scopoletin, which has been shown to lower high-blood pressure by dilating constricted blood vessels. Noni also stimulates the body to produce nitric oxide and it relaxes and expands blood vessels, alleviating stress on the arteries and the heart providing valuable benefits for improved health*.
4. The digestive tract – Noni aids the digestive enzymes to efficiently break down food more thoroughly to absorb nutrients taken into the body from the foods eaten*.
5. Emotional and mental well-being – Noni is believed to boost serotonin in the brain that has been shown to aid in clearer thinking, better focus and concentration and an elevation in mood and sense of well-being*.
25,00 noni juice drinkers
An in-depth study of Noni juice and it's medicinal health benefits was conducted
by Johns Hopkins trained Physician Dr. Neil Solomon who gathered from more than
1,227 health professionals representing over 25,314 noni juice drinkers from over
80 countries who received positive results by drinking Noni juice. His researched
focused on TAHITIAN NONI™ juice because at the time of his study had the
largest known base of Noni juice consumers.We can only wonder how much
higher the "% Helped" in his research would have been if he sampled people
who drank 100% pure NONI juice, rather than a reconstituted Noni juice
blend containing only 89% Noni fruit juice, supplemented with other fruit
concentrate fillers. We present his findings here for educational purposes.
Editions, Decreased Symptoms Total # %Helped
1. Allergy 3,198 86%
2. Arthritis 1,675 78%
3. Asthma 8,077 71%
4. Cancer 2,188 69%
. CFIDS, Fibromyalgia 3,524 77%
6. Depression 1,512 80%
7. Diabetics, Types 1 & 2 5,575 82%
8. Digestion 3,171 90%
9. Energy, increased 16,056 90%
10. Heart Disease 2,158 76%
11. High Blood Pressure, decreased 1,869 84%
12. HIV 150 55%
13. Immune System 3,707 77%
14. Kidney Disease 3,764 67%
15. Menstruation 3,798 79%
16. Mental Acuity, increased alertness 5,543 73%
17. Multiple Sclerosis 25
18. Muscle, increased body building 1,216 70%
19. Obesity, lost some excess weight 5,526 72%
20. Pain, including headaches 6,828 86%
21. Parkinson's Disease 25 52%
22. Respiratory Problems 3,857 72%
23. Skin and Hair Problems 877 78%
24. Sexual Enhancement increased 2,984 84%
25. Sleep, improved 2,025 75%
26. Smoking, stopped 876 56%
27. Stress, coped better 6,743 74%
28. Stroke 1,806 53%
29. Well-being, felt better 7,879 80%
Sunday, October 24, 2010
enzimnoni-mengkudu | 7:54 PM |
FED-NONI SOLVE THE PROBLEM OF BLOOD DISEASES CANCER, HEART DISEASE, STROKE, DIABETES, AFRODIASIAK, OBESITY, HYPERTENSION, SLEEP PROBLEMS, PRESSURE, allergic, digestive, BREATHING, TIRED, BRAIN FUNCTION DISORDERS, KIDNEY.
BSY-NONI-MENGKUDU
Noni juice has benefited the people of the South Pacific Islands for the past 2,000 years to aid a wide-range of health conditions to include: immune problems, joint pain, infection, colds, digestive disorders, injuries and inflammation.*Clinical researchers have identified well over 150 nutraceuticals in Noni fruit juice that have therapeutic value in the human body. Fresh-pressed Noni juice includes a potent mixture of nature’s most powerful phytonutrients and antioxidant that actively neutralize cell-damaging “free radicals” created in your body.
Top 5 Health Benefits Derived from 100% Pure NONI:
1. Anti-inflammation – Researchers from the University of Hawaii found Noni fruit juice to have inflammation-reducing constituents and the ability to suppress the COX-2 enzyme responsible for inflammation and pain.*
2. The immune system – Noni juice is a powerful natural food supplement to add to your diet because of its ability to stimulate your immune system into action. By drinking Noni juice daily, your body’s immune system is optimized to respond against the invasion of outside bacteria, germs and viruses as it fights them off and protects you from infection*.
3. The circulatory and cardiovascular systems – Noni fruit juice contains scopoletin, which has been shown to lower high-blood pressure by dilating constricted blood vessels. Noni also stimulates the body to produce nitric oxide and it relaxes and expands blood vessels, alleviating stress on the arteries and the heart providing valuable benefits for improved health*.
4. The digestive tract – Noni aids the digestive enzymes to efficiently break down food more thoroughly to absorb nutrients taken into the body from the foods eaten*.
5. Emotional and mental well-being – Noni is believed to boost serotonin in the brain that has been shown to aid in clearer thinking, better focus and concentration and an elevation in mood and sense of well-being*.
nditions, Decreased Symptoms Total # % Helped
Allergy 3,198 86%
Arthritis 1,675 78%
Asthma 8,077 71%
Cancer 2,188 69%
CFIDS, Fibromyalgia 3,524 77%
Depression 1,512 80%
Diabetics, Types 1 & 2 5,575 82%
Digestion 3,171 90%
Energy, increased 16,056 90%
Heart Disease 2,158 76%
High Blood Pressure, decreased 1,869 84%
HIV 150 55%
Immune System 3,707 77%
Kidney Disease 3,764 67%
Menstruation 3,798 79%
Mental Acuity, increased alertness 5,543 73%
Multiple Sclerosis 25 52%
Muscle, increased body building 1,216 70%
Obesity, lost some excess weight 5,526 72%
Pain, including headaches 6,828 86%
Parkinson's Disease 25 52%
Respiratory Problems 3,857 72%
Skin and Hair Problems 877 78%
Sexual Enhancement increased 2,984 84%
Sleep, improved 2,025 75%
Smoking, stopped 876 56%
Stress, coped better 6,743 74%
Stroke 1,806 53%
Well-being, felt better 7,879 80%
##########################################
Noni is a type of mulberry that produces a pungent, bitter juice packed with vitamins, minerals, amino acids and antioxidants. The popularity of this juice has risen in the last two decades, but has been used for centuries in some South Pacific and Asian countries. This juice offers numerous health benefits, does not interact with medications and has no known side effects.
BSY-NONI-MENGKUDU
Noni juice has benefited the people of the South Pacific Islands for the past 2,000 years to aid a wide-range of health conditions to include: immune problems, joint pain, infection, colds, digestive disorders, injuries and inflammation.*Clinical researchers have identified well over 150 nutraceuticals in Noni fruit juice that have therapeutic value in the human body. Fresh-pressed Noni juice includes a potent mixture of nature’s most powerful phytonutrients and antioxidant that actively neutralize cell-damaging “free radicals” created in your body.
Top 5 Health Benefits Derived from 100% Pure NONI:
1. Anti-inflammation – Researchers from the University of Hawaii found Noni fruit juice to have inflammation-reducing constituents and the ability to suppress the COX-2 enzyme responsible for inflammation and pain.*
2. The immune system – Noni juice is a powerful natural food supplement to add to your diet because of its ability to stimulate your immune system into action. By drinking Noni juice daily, your body’s immune system is optimized to respond against the invasion of outside bacteria, germs and viruses as it fights them off and protects you from infection*.
3. The circulatory and cardiovascular systems – Noni fruit juice contains scopoletin, which has been shown to lower high-blood pressure by dilating constricted blood vessels. Noni also stimulates the body to produce nitric oxide and it relaxes and expands blood vessels, alleviating stress on the arteries and the heart providing valuable benefits for improved health*.
4. The digestive tract – Noni aids the digestive enzymes to efficiently break down food more thoroughly to absorb nutrients taken into the body from the foods eaten*.
5. Emotional and mental well-being – Noni is believed to boost serotonin in the brain that has been shown to aid in clearer thinking, better focus and concentration and an elevation in mood and sense of well-being*.
nditions, Decreased Symptoms Total # % Helped
Allergy 3,198 86%
Arthritis 1,675 78%
Asthma 8,077 71%
Cancer 2,188 69%
CFIDS, Fibromyalgia 3,524 77%
Depression 1,512 80%
Diabetics, Types 1 & 2 5,575 82%
Digestion 3,171 90%
Energy, increased 16,056 90%
Heart Disease 2,158 76%
High Blood Pressure, decreased 1,869 84%
HIV 150 55%
Immune System 3,707 77%
Kidney Disease 3,764 67%
Menstruation 3,798 79%
Mental Acuity, increased alertness 5,543 73%
Multiple Sclerosis 25 52%
Muscle, increased body building 1,216 70%
Obesity, lost some excess weight 5,526 72%
Pain, including headaches 6,828 86%
Parkinson's Disease 25 52%
Respiratory Problems 3,857 72%
Skin and Hair Problems 877 78%
Sexual Enhancement increased 2,984 84%
Sleep, improved 2,025 75%
Smoking, stopped 876 56%
Stress, coped better 6,743 74%
Stroke 1,806 53%
Well-being, felt better 7,879 80%
##########################################
Medical Benefits of Noni Juice
Noni is a type of mulberry that produces a pungent, bitter juice packed with vitamins, minerals, amino acids and antioxidants. The popularity of this juice has risen in the last two decades, but has been used for centuries in some South Pacific and Asian countries. This juice offers numerous health benefits, does not interact with medications and has no known side effects.
Vitamins, Minerals and Amino Acids
- Noni juice contains vitamins A and C, niacin and calcium. It also has a high amount of potassium. For this reason, the Mayo Clinic recommends that individuals use caution if they have a kidney disease or are taking potassium-sparing diuretics, angiotensin-converting enzyme inhibitors or angiotension II receptor blockers, as they may make the potassium levels in the body rise to a dangerous level.
Pain Reducer
- Noni acts as an anti-inflammatory agent to reduce pain associated with arthritis and joint discomfort. Noni also protects the kidneys, liver and stomach as it works, which is something that many pharmaceutical pain relievers do not offer.
Pineal Gland Stimulation
- The pineal gland helps regulate several glands throughout the body. If the pineal gland is not functioning properly, the other glands may also have the same effect. The pineal gland produces melanin, a helpful pigment that is found throughout the body. Noni juice stimulates the production of this pigment within the pineal gland.
Digestive Functioning
- Digestive functioning shows improvement after taking noni juice. The juice helps to clean and remove unwanted parasites from the digestive tract. Individuals that suffer from ulcers, constipation, diarrhea, food poisoning and irritable bowel syndrome may benefit from taking Noni.
Antioxidant Benefits
- Noni juice is a powerful antioxidant that helps rid the body of free radicals. Free radicals are particles that are formed when weak bonds of molecules in the body break apart and are released into the body. These free radicals are unstable by nature and attack nearby cells in efforts to balance themselves out. This can cause damage to various cells throughout the body and DNA. Noni juice helps balance the free radicals by giving them the molecular stability they need to cease this damaging behavior.
Alkalinity Balancing
- Noni helps balance out the alkalinity within the body. Diseases flourish and tissues can get damaged in an environment that is too acidic.
Blood Sugar Regulation
- Noni aids the pancreas in regulating and stabilizing blood sugar levels. This is beneficial for people who suffer from diabetes and hypoglycemia.
Macular Generation
- The macular is located in the back side of the eye and contains a pigment called melanin. If this pigment is lost, this is called macular degeneration and results in blindness. Noni helps add more pigment to this area, resulting in the regeneration of cells which helps reverse the condition.
Uterus Health
- Women that are experiencing fibroids in the uterus have reported reduction of symptoms after drinking noni juice. Other women have reported that their menstruation cycle normalizes and produces less cramping.
Medical Benefits of Noni Juice
Noni is a type of mulberry that produces a pungent, bitter juice packed with vitamins, minerals, amino acids and antioxidants. The popularity of this juice has risen in the last two decades, but has been used for centuries in some South Pacific and Asian countries. This juice offers numerous health benefits, does not interact with medications and has no known side effects.Vitamins, Minerals and Amino Acids
- Noni juice contains vitamins A and C, niacin and calcium. It also has a high amount of potassium. For this reason, the Mayo Clinic recommends that individuals use caution if they have a kidney disease or are taking potassium-sparing diuretics, angiotensin-converting enzyme inhibitors or angiotension II receptor blockers, as they may make the potassium levels in the body rise to a dangerous level.
Pain Reducer
- Noni acts as an anti-inflammatory agent to reduce pain associated with arthritis and joint discomfort. Noni also protects the kidneys, liver and stomach as it works, which is something that many pharmaceutical pain relievers do not offer.
Pineal Gland Stimulation
- The pineal gland helps regulate several glands throughout the body. If the pineal gland is not functioning properly, the other glands may also have the same effect. The pineal gland produces melanin, a helpful pigment that is found throughout the body. Noni juice stimulates the production of this pigment within the pineal gland.
Digestive Functioning
- Digestive functioning shows improvement after taking noni juice. The juice helps to clean and remove unwanted parasites from the digestive tract. Individuals that suffer from ulcers, constipation, diarrhea, food poisoning and irritable bowel syndrome may benefit from taking Noni.
Antioxidant Benefits
- Noni juice is a powerful antioxidant that helps rid the body of free radicals. Free radicals are particles that are formed when weak bonds of molecules in the body break apart and are released into the body. These free radicals are unstable by nature and attack nearby cells in efforts to balance themselves out. This can cause damage to various cells throughout the body and DNA. Noni juice helps balance the free radicals by giving them the molecular stability they need to cease this damaging behavior.
Alkalinity Balancing
- Noni helps balance out the alkalinity within the body. Diseases flourish and tissues can get damaged in an environment that is too acidic.
Blood Sugar Regulation
- Noni aids the pancreas in regulating and stabilizing blood sugar levels. This is beneficial for people who suffer from diabetes and hypoglycemia.
Macular Generation
- The macular is located in the back side of the eye and contains a pigment called melanin. If this pigment is lost, this is called macular degeneration and results in blindness. Noni helps add more pigment to this area, resulting in the regeneration of cells which helps reverse the condition.
Uterus Health
- Women that are experiencing fibroids in the uterus have reported reduction of symptoms after drinking noni juice. Other women have reported that their menstruation cycle normalizes and produces less cramping.
Noni Juice Pros & Cons
Noni juice has grown in popularity, and many distributors have begun producing it. Purists believe the best noni juice comes from the pollutant-free volcanic soils of the South Pacific. The harvesting of the noni fruit is imperative in maintaining the healthiest benefits.
History
- The Polynesians first discovered the medical uses of noni juice more than 2,000 years ago. In 2003, the European Commission approved noni juice as a novel food and allowed it to be commercialized. New foods in Europe are stringently tested for safety.
Uses
- Noni juice is used for those with arthritis, immune disorders, colds, cancer, depression, hypertension, high blood pressure, skin infections and pain. It contains antibacterial compounds that help guard against infections and diseases.
Vitamins
- Noni juice is rich in vitamin A, calcium, sodium, vitamin C, niacin and potassium. It also contains 10 essential vitamins, seven dietary mineral and 18 amino acids. Noni juice contains xeronine, an alkaloid needed for proper cell function.
Side Effects
- Like other natural products, noni juice does have some side effects. These include coughing, headaches, bloating, gas, diarrhea, joint pain, foul breath, rashes, fatigue and heavy periods in women.
Considerations
Most of these side effects are short-lived and occurred in less than 10 percent of those who consumed the juice. Also, those experiencing side effects might have had an allergic reaction to the fruit.Warnings
- Noni juice typically has an unpleasant taste when it isn't flavored with additives. Those looking for nutritional benefits may prefer to look to other more palatable fruit juices or pursue the type of noni juice with flavor additives.
Noni juice can be high in potassium, which can prove dangerous for those with kidney disease, as it can cause potassium levels in the blood to get dangerously high, a condition called hyperkalemia.
Thursday, April 1, 2010
enzimnoni-mengkudu | 7:40 PM |
Tekanan Darah Tinggi (hipertensi) adalah suatu peningkatan tekanan darah di dalam arteri.
Secara umum, hipertensi merupakan suatu keadaan tanpa gejala, dimana tekanan yang abnormal tinggi di dalam arteri menyebabkan meningkatnya resiko terhadap stroke, aneurisma, gagal jantung, serangan jantung dan kerusakan ginjal.
Pada pemeriksaan tekanan darah akan didapat dua angka. Angka yang lebih tinggi diperoleh pada saat jantung berkontraksi (sistolik), angka yang lebih rendah diperoleh pada saat jantung berelaksasi (diastolik).
Tekanan darah ditulis sebagai tekanan sistolik garis miring tekanan diastolik, misalnya 120/80 mmHg, dibaca seratus dua puluh per delapan puluh.
Dikatakan tekanan darah tinggi jika pada saat duduk tekanan sistolik mencapai 140 mmHg atau lebih, atau tekanan diastolik mencapai 90 mmHg atau lebih, atau keduanya.
Pada tekanan darah tinggi, biasanya terjadi kenaikan tekanan sistolik dan diastolik.
Pada hipertensi sistolik terisolasi, tekanan sistolik mencapai 140 mmHg atau lebih, tetapi tekanan diastolik kurang dari 90 mmHg dan tekanan diastolik masih dalam kisaran normal. Hipertensi ini sering ditemukan pada usia lanjut.
Sejalan dengan bertambahnya usia, hampir setiap orang mengalami kenaikan tekanan darah; tekanan sistolik terus meningkat sampai usia 80 tahun dan tekanan diastolik terus meningkat sampai usia 55-60 tahun, kemudian berkurang secara perlahan atau bahkan menurun drastis.
Hipertensi maligna adalah hipertensi yang sangat parah, yang bila tidak diobati, akan menimbulkan kematian dalam waktu 3-6 bulan.
Hipertensi ini jarang terjadi, hanya 1 dari setiap 200 penderita hipertensi.
Tekanan darah dalam kehidupan seseorang bervariasi secara alami. Bayi dan anak-anak secara normal memiliki tekanan darah yang jauh lebih rendah daripada dewasa.
Tekanan darah juga dipengaruhi oleh aktivitas fisik, dimana akan lebih tinggi pada saat melakukan aktivitas dan lebih rendah ketika beristirahat.
Tekanan darah dalam satu hari juga berbeda; paling tinggi di waktu pagi hari dan paling rendah pada saat tidur malam hari.
Klasifikasi Tekanan Darah Pada Dewasa
Kategori Tekanan Darah Sistolik Tekanan Darah Diastolik
Normal Dibawah 130 mmHg Dibawah 85 mmHg
Normal tinggi 130-139 mmHg 85-89 mmHg
Stadium 1
(Hipertensi ringan) 140-159 mmHg 90-99 mmHg
Stadium 2
(Hipertensi sedang) 160-179 mmHg 100-109 mmHg
Stadium 3
(Hipertensi berat) 180-209 mmHg 110-119 mmHg
Stadium 4
(Hipertensi maligna) 210 mmHg atau lebih 120 mmHg atau lebih
PENGENDALIAN TEKANAN DARAH
Meningkatnya tekanan darah di dalam arteri bisa terjadi melalui beberapa cara:
1. Jantung memompa lebih kuat sehingga mengalirkan lebih banyak cairan pada setiap detiknya
2. Arteri besar kehilangan kelenturannya dan menjadi kaku, sehingga mereka tidak dapat mengembang pada saat jantung memompa darah melalui arteri tersebut. Karena itu darah pada setiap denyut jantung dipaksa untuk melalui pembuluh yang sempit daripada biasanya dan menyebabkan naiknya tekanan. Inilah yang terjadi pada usia lanjut, dimana dinding arterinya telah menebal dan kaku karena arteriosklerosis.
Dengan cara yang sama, tekanan darah juga meningkat pada saat terjadi vasokonstriksi, yaitu jika arteri kecil (arteriola) untuk sementara waktu mengkerut karena perangsangan saraf atau hormon di dalam darah.
3. Bertambahnya cairan dalam sirkulasi bisa menyebabkan meningkatnya tekanan darah. Hal ini terjadi jika terdapat kelainan fungsi ginjal sehingga tidak mampu membuang sejumlah garam dan air dari dalam tubuh. Volume darah dalam tubuh meningkat, sehingga tekanan darah juga meningkat.
Sebaliknya, jika:
- aktivitas memompa jantung berkurang
- arteri mengalami pelebaran
- banyak cairan keluar dari sirkulasi
maka tekanan darah akan menurun.
Penyesuaian terhadap faktor-faktor tersebut dilaksanakan oleh perubahan di dalam fungsi ginjal dan sistem saraf otonom (bagian dari sistem saraf yang mengatur berbagai fungsi tubuh secara otomatis).
1. Perubahan fungsi ginjal
Ginjal mengendalikan tekanan darah melalui beberapa cara:
- Jika tekanan darah meningkat, ginjal akan menambah pengeluaran garam dan air, yang akan menyebabkan berkurangnya volume darah dan mengembalikan tekana darah ke normal.
- Jika tekanan darah menurun, ginjal akan mengurangi pembuangan garam dan air, sehingga volume darah bertambah dan tekanan darah kembali ke normal.
- Ginjal juga bisa meningkatkan tekanan darah dengan menghasilkan enzim yang disebut renin, yang memicu pembentukan hormon angiotensi, yang selanjutnya akan memicu pelepasan hormon aldosteron.
Ginjal merupakan organ penting dalam mengendalikan tekanan darah; karena itu berbagai penyakit dan kelainan pda ginjal bisa menyebabkan terjadinya tekanan darah tinggi.
Misalnya penyempitan arteri yang menuju ke salah satu ginjal (stenosis arteri renalis) bisa menyebabkan hipertensi.
Peradangan dan cedera pada salah satu atau kedua ginjal juga bisa menyebabkan naiknya tekanan darah.
2. Sistem saraf simpatis merupakan bagian dari sistem saraf otonom, yang untuk sementara waktu akan:
- meningkatkan tekanan darah selama respon fight-or-flight (reaksi fisik tubuh terhadap ancaman dari luar)
- meningkatkan kecepatan dan kekuatan denyut jantung; juga mempersempit sebagian besar arteriola, tetapi memperlebar arteriola di daerah tertentu (misalnya otot rangka, yang memerlukan pasokan darah yang lebih banyak)
- mengurangi pembuangan air dan garam oleh ginjal, sehingga akan meningkatkan volume darah dalam tubuh
- melepaskan hormon epinefrin (adrenalin) dan norepinefrin (noradrenalin), yang merangsang jantung dan pembuluh darah.
PENYEBAB
Pada sekitar 90% penderita hipertensi, penyebabnya tidak diketahui dan keadaan ini dikenal sebagai hipertensi esensial atau hipertensi primer.
Hipertensi esensial kemungkinan memiliki banyak penyebab; beberapa perubahan pada jantung dan pembuluh darah kemungkinan bersama-sama menyebabkan meningkatnya tekanan darah.
Jika penyebabnya diketahui, maka disebut hipertensi sekunder.
Pada sekitar 5-10% penderita hipertensi, penyebabnya adalah penyakit ginjal.
Pada sekitar 1-2%, penyebabnya adalah kelainan hormonal atau pemakaian obat tertentu (misalnya pil KB).
Penyebab hipertensi lainnya yang jarang adalah feokromositoma, yaitu tumor pada kelenjar adrenal yang menghasilkan hormon epinefrin (adrenalin) atau norepinefrin (noradrenalin).
Kegemukan (obesitas), gaya hidup yang tidak aktif (malas berolah raga), stres, alkohol atau garam dalam makanan; bisa memicu terjadinya hipertensi pada orang-orang memiliki kepekaan yang diturunkan.
Stres cenderung menyebabkan kenaikan tekanan darah untuk sementara waktu, jika stres telah berlalu, maka tekanan darah biasanya akan kembali normal.
Beberapa penyebab terjadinya hipertensi sekunder:
1. Penyakit Ginjal
- Stenosis arteri renalis
- Pielonefritis
- Glomerulonefritis
- Tumor-tumor ginjal
- Penyakit ginjal polikista (biasanya diturunkan)
- Trauma pada ginjal (luka yang mengenai ginjal)
- Terapi penyinaran yang mengenai ginjal
2. Kelainan Hormonal
- Hiperaldosteronisme
- Sindroma Cushing
- Feokromositoma
3. Obat-obatan
- Pil KB
- Kortikosteroid
- Siklosporin
- Eritropoietin
- Kokain
- Penyalahgunaan alkohol
- Kayu manis (dalam jumlah sangat besar)
4. Penyebab Lainnya
- Koartasio aorta
- Preeklamsi pada kehamilan
- Porfiria intermiten akut
- Keracunan timbal akut.
GEJALA
Pada sebagian besar penderita, hipertensi tidak menimbulkan gejala; meskipun secara tidak sengaja beberapa gejala terjadi bersamaan dan dipercaya berhubungan dengan tekanan darah tinggi (padahal sesungguhnya tidak).
Gejala yang dimaksud adalah sakit kepala, perdarahan dari hidung, pusing, wajah kemerahan dan kelelahan; yang bisa saja terjadi baik pada penderita hipertensi, maupun pada seseorang dengan tekanan darah yang normal.
Jika hipertensinya berat atau menahun dan tidak diobati, bisa timbul gejala berikut:
- sakit kepala
- kelelahan
- mual
- muntah
- sesak nafas
- gelisah
- pandangan menjadi kabur
yang terjadi karena adanya kerusakan pada otak, mata, jantung dan ginjal.
Kadang penderita hipertensi berat mengalami penurunan kesadaran dan bahkan koma karena terjadi pembengkakan otak.
Keadaan ini disebut ensefalopati hipertensif, yang memerlukan penanganan segera.
DIAGNOSA
Tekanan darah diukur setelah seseorang duduk atau berbaring selama 5 menit.
Angka 140/90 mmHg atau lebih dapat diartikan sebagai hipertensi, tetapi diagnosis tidak dapat ditegakkan hanya berdasarkan satu kali pengukuran.
Jika pada pengukuran pertama memberikan hasil yang tinggi, maka tekanan darah diukur kembali dan kemudian diukur sebanyak 2 kali pada 2 hari berikutnya untuk meyakinkan adanya hipertensi.
Hasil pengukuran bukan hanya menentukan adanya tekanan darah tinggi, tetepi juga digunakan untuk menggolongkan beratnya hipertensi.
Setelah diagnosis ditegakkan, dilakukan pemeriksaan terhadap organ utama, terutama pembuluh darah, jantung, otak dan ginjal.
Retina (selaput peka cahaya pada permukaan dalam bagian belakang mata) merupakan satu-satunya bagian tubuh yang secara langsung bisa menunjukkan adanya efek dari hipertensi terhadap arteriola (pembuluh darah kecil). Dengan anggapan bahwa perubahan yang terjadi di dalam retina mirip dengan perubahan yang terjadi di dalam pembuluh darah lainnya di dalam tubuh, seperti ginjal.
Untuk memeriksa retina, digunakan suatu oftalmoskop. Dengan menentukan derajat kerusakan retina (retinopati), maka bisa ditentukan beratnya hipertensi.
Perubahan di dalam jantung, terutama pembesaran jantung, bisa ditemukan pada elektrokardiografi (EKG) dan foto rontgen dada.
Pada stadium awal, perubahan tersebut bisa ditemukan melalui pemeriksaan ekokardiografi (pemeriksaan dengan gelombang ultrasonik untuk menggambarkan keadaan jantung).
Bunyi jantung yang abnormal (disebut bunyi jantung keempat), bisa didengar melalui stetoskop dan merupakan perubahan jantung paling awal yang terjadi akibat tekanan darah tinggi.
Petunjuk awal adanya kerusakan ginjal bisa diketahui terutama melalui pemeriksaan air kemih.
Adanya sel darah dan albumin (sejenis protein) dalam air kemih bisa merupakan petunjuk terjadinya kerusakan ginjal.
Pemeriksaan untuk menentukan penyebab dari hipertensi terutama dilakukan pada penderita usia muda.
Pemeriksaan ini bisa berupa rontgen dan radioisotop ginjal, rontgen dada serta pemeriksaan darah dan air kemih untuk hormon tertentu.
Untuk menemukan adanya kelainan ginjal, ditanyakan mengenai riwayat kelainan ginjal sebelumnya.
Sebuah stetoskop ditempelkan diatas perut untuk mendengarkan adanya bruit (suara yang terjadi karena darah mengalir melalui arteri yang menuju ke ginjal, yang mengalami penyempitan).
Dilakukan analisa air kemih dan rontgen atau USG ginjal.
Jika penyebabnya adalah feokromositoma, maka di dalam air kemih bisa ditemukan adanya bahan-bahan hasil penguraian hormon epinefrin dan norepinefrin.
Biasanya hormon tersebut juga menyebabkan gejala sakit kepala, kecemasan, palpitasi (jantung berdebar-debar), keringat yang berlebihan, tremor (gemetar) dan pucat.
Penyebab lainnya bisa ditemukan melalui pemeriksaan rutin tertentu.
Misalnya mengukur kadar kalium dalam darah bisa membantu menemukan adanya hiperaldosteronisme dan mengukur tekanan darah pada kedua lengan dan tungkai bisa membantu menemukan adanya koartasio aorta.
PENGOBATAN
Hipertensi esensial tidak dapat diobati tetapi dapat diberikan pengobatan untuk mencegah terjadinya komplikasi.
Langkah awal biasanya adalah merubah pola hidup penderita:
1. Penderita hipertensi yang mengalami kelebihan berat badan dianjurkan untuk menurunkan berat badannya sampai batas ideal.
2. Merubah pola makan pada penderita diabetes, kegemukan atau kadar kolesterol darah tinggi.
Mengurangi pemakaian garam sampai kurang dari 2,3 gram natrium atau 6 gram natrium klorida setiap harinya (disertai dengan asupan kalsium, magnesium dan kalium yang cukup) dan mengurangi alkohol.
3. Olah raga aerobik yang tidak terlalu berat.
Penderita hipertensi esensial tidak perlu membatasi aktivitasnya selama tekanan darahnya terkendali.
4. Berhenti merokok.
Secara umum, hipertensi merupakan suatu keadaan tanpa gejala, dimana tekanan yang abnormal tinggi di dalam arteri menyebabkan meningkatnya resiko terhadap stroke, aneurisma, gagal jantung, serangan jantung dan kerusakan ginjal.
Pada pemeriksaan tekanan darah akan didapat dua angka. Angka yang lebih tinggi diperoleh pada saat jantung berkontraksi (sistolik), angka yang lebih rendah diperoleh pada saat jantung berelaksasi (diastolik).
Tekanan darah ditulis sebagai tekanan sistolik garis miring tekanan diastolik, misalnya 120/80 mmHg, dibaca seratus dua puluh per delapan puluh.
Dikatakan tekanan darah tinggi jika pada saat duduk tekanan sistolik mencapai 140 mmHg atau lebih, atau tekanan diastolik mencapai 90 mmHg atau lebih, atau keduanya.
Pada tekanan darah tinggi, biasanya terjadi kenaikan tekanan sistolik dan diastolik.
Pada hipertensi sistolik terisolasi, tekanan sistolik mencapai 140 mmHg atau lebih, tetapi tekanan diastolik kurang dari 90 mmHg dan tekanan diastolik masih dalam kisaran normal. Hipertensi ini sering ditemukan pada usia lanjut.
Sejalan dengan bertambahnya usia, hampir setiap orang mengalami kenaikan tekanan darah; tekanan sistolik terus meningkat sampai usia 80 tahun dan tekanan diastolik terus meningkat sampai usia 55-60 tahun, kemudian berkurang secara perlahan atau bahkan menurun drastis.
Hipertensi maligna adalah hipertensi yang sangat parah, yang bila tidak diobati, akan menimbulkan kematian dalam waktu 3-6 bulan.
Hipertensi ini jarang terjadi, hanya 1 dari setiap 200 penderita hipertensi.
Tekanan darah dalam kehidupan seseorang bervariasi secara alami. Bayi dan anak-anak secara normal memiliki tekanan darah yang jauh lebih rendah daripada dewasa.
Tekanan darah juga dipengaruhi oleh aktivitas fisik, dimana akan lebih tinggi pada saat melakukan aktivitas dan lebih rendah ketika beristirahat.
Tekanan darah dalam satu hari juga berbeda; paling tinggi di waktu pagi hari dan paling rendah pada saat tidur malam hari.
Klasifikasi Tekanan Darah Pada Dewasa
Kategori Tekanan Darah Sistolik Tekanan Darah Diastolik
Normal Dibawah 130 mmHg Dibawah 85 mmHg
Normal tinggi 130-139 mmHg 85-89 mmHg
Stadium 1
(Hipertensi ringan) 140-159 mmHg 90-99 mmHg
Stadium 2
(Hipertensi sedang) 160-179 mmHg 100-109 mmHg
Stadium 3
(Hipertensi berat) 180-209 mmHg 110-119 mmHg
Stadium 4
(Hipertensi maligna) 210 mmHg atau lebih 120 mmHg atau lebih
PENGENDALIAN TEKANAN DARAH
Meningkatnya tekanan darah di dalam arteri bisa terjadi melalui beberapa cara:
1. Jantung memompa lebih kuat sehingga mengalirkan lebih banyak cairan pada setiap detiknya
2. Arteri besar kehilangan kelenturannya dan menjadi kaku, sehingga mereka tidak dapat mengembang pada saat jantung memompa darah melalui arteri tersebut. Karena itu darah pada setiap denyut jantung dipaksa untuk melalui pembuluh yang sempit daripada biasanya dan menyebabkan naiknya tekanan. Inilah yang terjadi pada usia lanjut, dimana dinding arterinya telah menebal dan kaku karena arteriosklerosis.
Dengan cara yang sama, tekanan darah juga meningkat pada saat terjadi vasokonstriksi, yaitu jika arteri kecil (arteriola) untuk sementara waktu mengkerut karena perangsangan saraf atau hormon di dalam darah.
3. Bertambahnya cairan dalam sirkulasi bisa menyebabkan meningkatnya tekanan darah. Hal ini terjadi jika terdapat kelainan fungsi ginjal sehingga tidak mampu membuang sejumlah garam dan air dari dalam tubuh. Volume darah dalam tubuh meningkat, sehingga tekanan darah juga meningkat.
Sebaliknya, jika:
- aktivitas memompa jantung berkurang
- arteri mengalami pelebaran
- banyak cairan keluar dari sirkulasi
maka tekanan darah akan menurun.
Penyesuaian terhadap faktor-faktor tersebut dilaksanakan oleh perubahan di dalam fungsi ginjal dan sistem saraf otonom (bagian dari sistem saraf yang mengatur berbagai fungsi tubuh secara otomatis).
1. Perubahan fungsi ginjal
Ginjal mengendalikan tekanan darah melalui beberapa cara:
- Jika tekanan darah meningkat, ginjal akan menambah pengeluaran garam dan air, yang akan menyebabkan berkurangnya volume darah dan mengembalikan tekana darah ke normal.
- Jika tekanan darah menurun, ginjal akan mengurangi pembuangan garam dan air, sehingga volume darah bertambah dan tekanan darah kembali ke normal.
- Ginjal juga bisa meningkatkan tekanan darah dengan menghasilkan enzim yang disebut renin, yang memicu pembentukan hormon angiotensi, yang selanjutnya akan memicu pelepasan hormon aldosteron.
Ginjal merupakan organ penting dalam mengendalikan tekanan darah; karena itu berbagai penyakit dan kelainan pda ginjal bisa menyebabkan terjadinya tekanan darah tinggi.
Misalnya penyempitan arteri yang menuju ke salah satu ginjal (stenosis arteri renalis) bisa menyebabkan hipertensi.
Peradangan dan cedera pada salah satu atau kedua ginjal juga bisa menyebabkan naiknya tekanan darah.
2. Sistem saraf simpatis merupakan bagian dari sistem saraf otonom, yang untuk sementara waktu akan:
- meningkatkan tekanan darah selama respon fight-or-flight (reaksi fisik tubuh terhadap ancaman dari luar)
- meningkatkan kecepatan dan kekuatan denyut jantung; juga mempersempit sebagian besar arteriola, tetapi memperlebar arteriola di daerah tertentu (misalnya otot rangka, yang memerlukan pasokan darah yang lebih banyak)
- mengurangi pembuangan air dan garam oleh ginjal, sehingga akan meningkatkan volume darah dalam tubuh
- melepaskan hormon epinefrin (adrenalin) dan norepinefrin (noradrenalin), yang merangsang jantung dan pembuluh darah.
PENYEBAB
Pada sekitar 90% penderita hipertensi, penyebabnya tidak diketahui dan keadaan ini dikenal sebagai hipertensi esensial atau hipertensi primer.
Hipertensi esensial kemungkinan memiliki banyak penyebab; beberapa perubahan pada jantung dan pembuluh darah kemungkinan bersama-sama menyebabkan meningkatnya tekanan darah.
Jika penyebabnya diketahui, maka disebut hipertensi sekunder.
Pada sekitar 5-10% penderita hipertensi, penyebabnya adalah penyakit ginjal.
Pada sekitar 1-2%, penyebabnya adalah kelainan hormonal atau pemakaian obat tertentu (misalnya pil KB).
Penyebab hipertensi lainnya yang jarang adalah feokromositoma, yaitu tumor pada kelenjar adrenal yang menghasilkan hormon epinefrin (adrenalin) atau norepinefrin (noradrenalin).
Kegemukan (obesitas), gaya hidup yang tidak aktif (malas berolah raga), stres, alkohol atau garam dalam makanan; bisa memicu terjadinya hipertensi pada orang-orang memiliki kepekaan yang diturunkan.
Stres cenderung menyebabkan kenaikan tekanan darah untuk sementara waktu, jika stres telah berlalu, maka tekanan darah biasanya akan kembali normal.
Beberapa penyebab terjadinya hipertensi sekunder:
1. Penyakit Ginjal
- Stenosis arteri renalis
- Pielonefritis
- Glomerulonefritis
- Tumor-tumor ginjal
- Penyakit ginjal polikista (biasanya diturunkan)
- Trauma pada ginjal (luka yang mengenai ginjal)
- Terapi penyinaran yang mengenai ginjal
2. Kelainan Hormonal
- Hiperaldosteronisme
- Sindroma Cushing
- Feokromositoma
3. Obat-obatan
- Pil KB
- Kortikosteroid
- Siklosporin
- Eritropoietin
- Kokain
- Penyalahgunaan alkohol
- Kayu manis (dalam jumlah sangat besar)
4. Penyebab Lainnya
- Koartasio aorta
- Preeklamsi pada kehamilan
- Porfiria intermiten akut
- Keracunan timbal akut.
GEJALA
Pada sebagian besar penderita, hipertensi tidak menimbulkan gejala; meskipun secara tidak sengaja beberapa gejala terjadi bersamaan dan dipercaya berhubungan dengan tekanan darah tinggi (padahal sesungguhnya tidak).
Gejala yang dimaksud adalah sakit kepala, perdarahan dari hidung, pusing, wajah kemerahan dan kelelahan; yang bisa saja terjadi baik pada penderita hipertensi, maupun pada seseorang dengan tekanan darah yang normal.
Jika hipertensinya berat atau menahun dan tidak diobati, bisa timbul gejala berikut:
- sakit kepala
- kelelahan
- mual
- muntah
- sesak nafas
- gelisah
- pandangan menjadi kabur
yang terjadi karena adanya kerusakan pada otak, mata, jantung dan ginjal.
Kadang penderita hipertensi berat mengalami penurunan kesadaran dan bahkan koma karena terjadi pembengkakan otak.
Keadaan ini disebut ensefalopati hipertensif, yang memerlukan penanganan segera.
DIAGNOSA
Tekanan darah diukur setelah seseorang duduk atau berbaring selama 5 menit.
Angka 140/90 mmHg atau lebih dapat diartikan sebagai hipertensi, tetapi diagnosis tidak dapat ditegakkan hanya berdasarkan satu kali pengukuran.
Jika pada pengukuran pertama memberikan hasil yang tinggi, maka tekanan darah diukur kembali dan kemudian diukur sebanyak 2 kali pada 2 hari berikutnya untuk meyakinkan adanya hipertensi.
Hasil pengukuran bukan hanya menentukan adanya tekanan darah tinggi, tetepi juga digunakan untuk menggolongkan beratnya hipertensi.
Setelah diagnosis ditegakkan, dilakukan pemeriksaan terhadap organ utama, terutama pembuluh darah, jantung, otak dan ginjal.
Retina (selaput peka cahaya pada permukaan dalam bagian belakang mata) merupakan satu-satunya bagian tubuh yang secara langsung bisa menunjukkan adanya efek dari hipertensi terhadap arteriola (pembuluh darah kecil). Dengan anggapan bahwa perubahan yang terjadi di dalam retina mirip dengan perubahan yang terjadi di dalam pembuluh darah lainnya di dalam tubuh, seperti ginjal.
Untuk memeriksa retina, digunakan suatu oftalmoskop. Dengan menentukan derajat kerusakan retina (retinopati), maka bisa ditentukan beratnya hipertensi.
Perubahan di dalam jantung, terutama pembesaran jantung, bisa ditemukan pada elektrokardiografi (EKG) dan foto rontgen dada.
Pada stadium awal, perubahan tersebut bisa ditemukan melalui pemeriksaan ekokardiografi (pemeriksaan dengan gelombang ultrasonik untuk menggambarkan keadaan jantung).
Bunyi jantung yang abnormal (disebut bunyi jantung keempat), bisa didengar melalui stetoskop dan merupakan perubahan jantung paling awal yang terjadi akibat tekanan darah tinggi.
Petunjuk awal adanya kerusakan ginjal bisa diketahui terutama melalui pemeriksaan air kemih.
Adanya sel darah dan albumin (sejenis protein) dalam air kemih bisa merupakan petunjuk terjadinya kerusakan ginjal.
Pemeriksaan untuk menentukan penyebab dari hipertensi terutama dilakukan pada penderita usia muda.
Pemeriksaan ini bisa berupa rontgen dan radioisotop ginjal, rontgen dada serta pemeriksaan darah dan air kemih untuk hormon tertentu.
Untuk menemukan adanya kelainan ginjal, ditanyakan mengenai riwayat kelainan ginjal sebelumnya.
Sebuah stetoskop ditempelkan diatas perut untuk mendengarkan adanya bruit (suara yang terjadi karena darah mengalir melalui arteri yang menuju ke ginjal, yang mengalami penyempitan).
Dilakukan analisa air kemih dan rontgen atau USG ginjal.
Jika penyebabnya adalah feokromositoma, maka di dalam air kemih bisa ditemukan adanya bahan-bahan hasil penguraian hormon epinefrin dan norepinefrin.
Biasanya hormon tersebut juga menyebabkan gejala sakit kepala, kecemasan, palpitasi (jantung berdebar-debar), keringat yang berlebihan, tremor (gemetar) dan pucat.
Penyebab lainnya bisa ditemukan melalui pemeriksaan rutin tertentu.
Misalnya mengukur kadar kalium dalam darah bisa membantu menemukan adanya hiperaldosteronisme dan mengukur tekanan darah pada kedua lengan dan tungkai bisa membantu menemukan adanya koartasio aorta.
PENGOBATAN
Hipertensi esensial tidak dapat diobati tetapi dapat diberikan pengobatan untuk mencegah terjadinya komplikasi.
Langkah awal biasanya adalah merubah pola hidup penderita:
1. Penderita hipertensi yang mengalami kelebihan berat badan dianjurkan untuk menurunkan berat badannya sampai batas ideal.
2. Merubah pola makan pada penderita diabetes, kegemukan atau kadar kolesterol darah tinggi.
Mengurangi pemakaian garam sampai kurang dari 2,3 gram natrium atau 6 gram natrium klorida setiap harinya (disertai dengan asupan kalsium, magnesium dan kalium yang cukup) dan mengurangi alkohol.
3. Olah raga aerobik yang tidak terlalu berat.
Penderita hipertensi esensial tidak perlu membatasi aktivitasnya selama tekanan darahnya terkendali.
4. Berhenti merokok.
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